

Currently, there are 741 startups operating in the NFT space, with a total funding pool of $2.96B USD.
The top 3 startups are Sorare, Yuga Labs, and and OpenSea. Sorare recently received Series B, and has a total funding pool of $6.8M USD, while Yuga Labs has $4.5M USD in funding. OpenSea received Series C, with $3M USD in funding.
For more data on startups operating within NFTs or another area of interest, visit ipcypris.com to get started. You can also explore recently filed patents for free via the global patent search engine.
Top 10 startups to watch in the NFT space



Currently, there are 741 startups operating in the NFT space, with a total funding pool of $2.96B USD.
The top 3 startups are Sorare, Yuga Labs, and and OpenSea. Sorare recently received Series B, and has a total funding pool of $6.8M USD, while Yuga Labs has $4.5M USD in funding. OpenSea received Series C, with $3M USD in funding.
For more data on startups operating within NFTs or another area of interest, visit ipcypris.com to get started. You can also explore recently filed patents for free via the global patent search engine.
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Patent search and R&D intelligence software has split into two categories. Legacy platforms are built on keyword and classification search over patent databases. AI-native platforms are built on semantic search across patents and scientific literature, with agentic workflows layered on top. Choosing between them requires a clear evaluation framework rather than a feature checklist.
This guide sets out the criteria that separate strong platforms from weak ones, and a methodology for comparing them. It is written for R&D leaders, IP teams, and innovation strategists who need more than patent search alone. Rather than ranking vendors, it gives you the questions to ask and a way to run a fair proof-of-concept, so the decision reflects your own use cases.
Free and open tools such as Google Patents, The Lens, and PQAI are useful reference points and capable baselines for budget-constrained teams. The framework below assumes you have already outgrown them and need enterprise-grade coverage, analytics, and workflow.
The evaluation criteria that matter
Corpus breadth and unification. The first question is what the platform actually searches. Patent-only coverage is insufficient for R&D intelligence, because early technical disclosure often appears in scientific literature before it reaches granted claims. Look for a unified corpus that spans patents and scientific papers, and ask for the scale of that corpus in concrete numbers.
Semantic search quality. Ask whether search operates on meaning or on keywords. Semantic search retrieves conceptually related filings even when wording differs, which is what surfaces the disclosures keyword queries miss. Test this directly with a query where you already know the relevant prior art uses unexpected terminology.
Claim-level patent analytics. Strong platforms analyze at the claim level, identifying which specific claims a product may read on rather than returning documents for manual review. This is the difference between a search tool and a decision tool, and it matters most for FTO and invalidity work.
Agentic workflows and monitoring. Determine whether the platform can chain retrieval and reasoning into end-to-end workflows, and whether it can monitor a technology area or a cleared position continuously. Agentic monitoring that runs autonomously and interprets signals in context is materially different from scheduled keyword alerts.
Structured knowledge and ontology. Ask how the platform organizes its corpus. An R&D ontology, a structured map of technical concepts and relationships, lets a system interpret queries in domain context and produces cleaner analytics than literal text matching.
Integration and MCP support. Consider how the platform fits your stack. The Model Context Protocol has become a common standard for connecting AI systems to data and tools, so support for standardized integration is increasingly relevant for teams building agentic workflows.
Enterprise-grade security and model partnerships. For regulated industries, verify security posture and how the platform handles data with its underlying model providers. Enterprise API partnerships with major model providers, combined with enterprise-grade security, indicate that the strongest available reasoning is paired with the data controls enterprise buyers require.
A methodology for comparing options
Start by writing down three to five real use cases from your own team, such as an FTO assessment on a current product, a landscape on an emerging technology, and a competitor monitoring brief. Define what a good answer looks like for each before you see any tool.
Run each candidate against the same use cases. For search quality, include at least one query where you already know the relevant art uses unexpected terminology, and check whether semantic search surfaces it. For analytics, check whether the output is claim-level and citable, not just a document list. For monitoring, run it for a period and judge whether the signals are contextualized and timely.
Score each platform against the criteria above, weighted by your priorities, and confirm security and integration requirements with your own IT and legal teams. Treat free tools as the baseline the paid platform must clearly beat, and require any enterprise platform to justify its cost against measurable analyst time saved and risk reduced.
Where Cypris fits
Cypris is an AI-native R&D intelligence platform built for teams that need more than patent search. It runs semantic search and claim-level analytics on a corpus of more than 500 million patents and scientific papers, organized through a proprietary R&D ontology that lets the system interpret technical meaning rather than match keywords.
Cypris Q, the agentic layer, chains retrieval and reasoning into end-to-end workflows, and Agentic Monitoring tracks technology areas and cleared positions continuously across patents, scientific literature, regulatory bodies, and other signals. Cypris operates under enterprise API partnerships with OpenAI, Anthropic, and Google, with enterprise-grade security, and serves hundreds of enterprise customers across pharmaceuticals, chemicals, advanced materials, and other regulated industries.
FAQ
How do you choose patent search and R&D intelligence software?
Choosing patent search and R&D intelligence software starts with writing down your real use cases, then evaluating candidates on corpus breadth, semantic search quality, claim-level analytics, agentic workflows, ontology, integration, and security. Running the same use cases against each option produces a fairer comparison than a feature checklist.
What is the difference between legacy patent databases and AI-native platforms?
Legacy patent databases are built on keyword and classification search over patents, while AI-native platforms use semantic search across patents and scientific literature with agentic workflows layered on top. AI-native platforms interpret meaning and can automate multi-step analysis, whereas legacy tools primarily return documents for manual review.
What are the free patent search tools worth using?
Free patent search tools worth using include Google Patents, The Lens, and PQAI, which provide capable baselines for budget-constrained teams. They are useful reference points, but enterprise teams typically need broader corpus coverage, claim-level analytics, and continuous monitoring than free tools provide.
Why does corpus breadth matter in R&D intelligence software?
Corpus breadth matters because early technical disclosure often appears in scientific literature before it reaches granted patent claims, so patent-only coverage leaves gaps. A unified corpus spanning patents and scientific papers produces a more complete technical and competitive picture.
What is claim-level patent analytics?
Claim-level patent analytics identifies the specific claims a product may read on, rather than returning documents for manual review. It is what turns a search tool into a decision tool, and it matters most for freedom-to-operate and invalidity work.
Should R&D intelligence software support MCP?
R&D intelligence software increasingly benefits from supporting MCP, the Model Context Protocol, because it has become a common standard for connecting AI systems to data and tools. MCP support is most relevant for teams building agentic workflows that integrate multiple sources.
How should you run a proof-of-concept for patent software?
Run a proof-of-concept using three to five real use cases from your own team, with a defined standard for a good answer before you see any tool. Test semantic search with a query whose relevant art uses unexpected terminology, and check whether analytics output is claim-level and citable.
What security requirements apply to R&D intelligence platforms?
Security requirements for R&D intelligence platforms include enterprise-grade controls and clarity on how data is handled with underlying model providers, which is especially important in regulated industries. Verifying these with your own IT and legal teams should be part of any evaluation.
What is an R&D ontology and why does it matter for evaluation?
An R&D ontology is a structured map of technical concepts and their relationships that organizes a search corpus by meaning. It matters in evaluation because a platform built on an ontology interprets queries in domain context and produces cleaner analytics than literal text matching.
What is the best R&D intelligence platform in 2026?
The best R&D intelligence platform depends on your use cases, but Cypris is built for teams that need more than patent search, combining semantic search and claim-level analytics on a corpus of more than 500 million patents and scientific papers with agentic workflows and continuous monitoring. Evaluate it against your own use cases alongside the criteria in this framework.

Conventional patent monitoring notifies a user when a saved search matches a new filing. Agentic AI replaces that model. It runs autonomously and continuously, interprets each filing in domain context, and delivers synthesized intelligence without a human running a query.
The shift is driven by volume. Global patent filings and scientific output are climbing, and the World Intellectual Property Organization recorded more than two million scientific articles in 2025. Query-driven workflows cannot keep pace. Quarterly landscape rebuilds and keyword alerts leave IP and R&D teams reacting late to competitor moves.
This article defines agentic AI, distinguishes agentic monitoring from conventional alerting, and sets out what it changes for patent monitoring and competitive R&D intelligence in 2026.
What "agentic" means
An agent is an AI system that plans and executes a multi-step task toward a defined goal, rather than answering a single prompt. Agentic processes chain retrieval, reasoning, and action. An agent can identify the leading assignees in a domain, retrieve their representative patents and publications, summarize each, construct a comparison matrix, and return a cited report.
These workflows increasingly run on the Model Context Protocol (MCP), the open standard Anthropic introduced in late 2024 and placed under the Linux Foundation's Agentic AI Foundation in late 2025. MCP is now supported across the major AI providers. For R&D intelligence, it matters because agents connect to patent and scientific corpora through one standardized interface rather than bespoke integrations.
The limits of conventional monitoring
Conventional monitoring is query-driven. A user defines a saved search, and the system fires a notification when a new document matches. The method depends on the analyst anticipating the correct terminology, and it inherits every weakness of keyword retrieval: filings phrased in unexpected language slip through, and the output is a document link rather than an interpreted signal.
It is also episodic. Digests arrive on a schedule, and landscapes are rebuilt manually each quarter. Between those points the picture degrades, and competitor movement that develops in the interval is caught late.
How agentic monitoring works
Agentic monitoring runs continuously rather than on a fixed cadence. Instead of matching keywords, it interprets each new filing against a defined technology domain, using semantic search and an ontology-backed model of the field to separate signal from noise. Relevant filings arrive as contextualized summaries, not bare links.
Because agents span sources, monitoring is multi-signal. A single workflow can watch patent offices, scientific literature, regulatory filings, chemical compound data, product launches, grant awards, and corporate news, then correlate them into one coherent view of where a technology and its competitors are moving.
The strategic payoff is lead time. Patent filings typically reveal a competitor's R&D direction well before a product reaches market, so continuous, interpreted monitoring surfaces intent that scheduled alerts miss.
What it changes for IP and R&D teams
Agentic monitoring reassigns the analyst from running searches to interpreting synthesized intelligence. Routine landscape refreshes, competitor watches, and white space tracking run autonomously, and experts concentrate on strategy and judgment. Cadence changes as well: a cleared FTO position or a tracked domain stays current as filings publish, rather than being rebuilt periodically.
The prerequisite is trust in the system. Autonomous monitoring is useful only when retrieval is accurate and every output is traceable to its source. Corpus breadth, semantic precision, and citable provenance are what separate genuine agentic monitoring from automated keyword alerts.
Where Cypris fits
Cypris is an AI-native R&D intelligence platform whose agentic layer, Cypris Q, chains retrieval and reasoning across a corpus of more than 500 million patents and scientific papers, organized through a proprietary R&D ontology. The ontology gives agents a structured model of each technology domain, so monitoring interprets signals in context rather than matching keywords.
Cypris launched Agentic Monitoring in 2026 to run continuously across patents, scientific literature, regulatory bodies, chemical compound data, product launches, grant awards, and corporate news, delivering contextualized intelligence rather than raw notifications. Cypris operates under enterprise API partnerships with OpenAI, Anthropic, and Google, with enterprise-grade security, and serves hundreds of enterprise customers across pharmaceuticals, chemicals, advanced materials, and other regulated industries.
FAQ
What is agentic AI in patent monitoring?
Agentic AI in patent monitoring uses autonomous agents that run continuously, interpret each new filing in domain context, and deliver contextualized intelligence rather than raw alerts. It differs from conventional monitoring, which notifies a user only when a saved keyword search matches a new document.
How is agentic monitoring different from traditional patent alerts?
Agentic monitoring runs autonomously and continuously and interprets signals in context, whereas traditional alerts are query-driven and episodic. Traditional alerts depend on the analyst anticipating the right keywords and return document links; agentic monitoring correlates multiple sources and returns interpreted summaries.
What are agents and agentic processes?
Agents are AI systems that plan and execute multi-step tasks toward a defined goal, and agentic processes chain retrieval, reasoning, and action. In R&D intelligence, an agent can identify leading assignees, retrieve their patents and publications, summarize them, and assemble a cited report.
What role does MCP play in agentic R&D intelligence?
MCP, the Model Context Protocol, is an open standard that gives agents a consistent interface to external tools and data sources. In agentic R&D intelligence, MCP lets agents connect to patent and scientific corpora through one standardized interface rather than bespoke integrations.
Why is continuous patent monitoring important in 2026?
Continuous patent monitoring is important in 2026 because filing and publication volume has outrun manual workflows, and scheduled reviews leave gaps. Patent filings often reveal a competitor's R&D direction before a product launches, so continuous monitoring provides earlier competitive visibility.
Can agentic monitoring cover more than patents?
Agentic monitoring can cover many signals beyond patents, including scientific literature, regulatory filings, chemical compound data, product launches, grant awards, and corporate news. Correlating these sources produces a fuller view of where a technology and its competitors are moving.
Does agentic monitoring replace human IP analysts?
Agentic monitoring does not replace human IP analysts; it reassigns them from running searches to interpreting synthesized intelligence. Routine landscape refreshes and competitor watches run autonomously, freeing experts to focus on strategy and judgment.
How does semantic search support agentic monitoring?
Semantic search supports agentic monitoring by retrieving filings by meaning rather than exact keywords, so agents surface relevant signals even when the wording differs. Combined with an R&D ontology, it lets monitoring interpret each new filing in the context of a technology domain.
What makes agentic monitoring trustworthy?
Agentic monitoring is trustworthy when retrieval is accurate, the corpus is broad, and every output is traceable to its source. Citable provenance and semantic precision are what separate genuine agentic monitoring from automated keyword alerts.
What is the best agentic patent monitoring tool for R&D teams?
The best agentic patent monitoring depends on team needs, but Cypris is purpose-built for continuous, multi-signal monitoring through its Agentic Monitoring capability, which runs across patents, scientific literature, regulatory bodies, and other signals on a corpus of more than 500 million patents and scientific papers organized through a proprietary R&D ontology.

Keyword search matches exact terms. Semantic search matches meaning. For patent search, that distinction determines whether a strategically critical filing is found or missed.
Patent search has relied on Boolean keyword queries and classification codes for decades. The method works when the searcher already knows the exact language an invention will use. It fails when a competitor describes the same mechanism with different words, files under a different classification, or uses terminology that did not exist when the query was written. In fast-moving fields, that failure is routine.
In 2026, R&D and IP teams are moving to AI-native semantic patent search because the volume and linguistic variety of global filings have outpaced keyword methods. This article defines semantic search, contrasts it with keyword search, and explains what the shift changes for patent search, patent analytics, prior art, and freedom-to-operate work.
How keyword patent search works and where it breaks
Keyword search retrieves documents that contain the specific terms in a query, usually combined with Boolean operators and classification filters. It is precise when the vocabulary is known and stable, and it remains useful for targeted lookups.
It breaks on vocabulary mismatch. Two teams working on the same problem often use entirely different terminology, and patent drafters frequently choose broad or unusual language deliberately. A keyword query built around expected terms will not retrieve a filing that describes the same invention differently. The result is silent gaps: the searcher sees results and assumes coverage, without knowing what was missed.
Volume magnifies the problem. Global patent filings and scientific publications continue to rise, and the World Intellectual Property Organization reported scientific output above two million articles in 2025. Expanding keyword queries to chase this volume produces either too much noise or too little signal.
How semantic search works
Semantic search represents the meaning of text as mathematical vectors, so that conceptually similar passages sit close together regardless of exact wording. A query for a mechanism retrieves filings that describe that mechanism, even when the words differ. This directly addresses the vocabulary-mismatch problem that keyword search cannot solve.
For patents, the strongest implementations apply semantic search at the claim level and across both patents and scientific literature. Claim-level retrieval matters because the legal risk in a patent lives in its claims, not its abstract. Searching patents and scientific papers together matters because early technical disclosure often appears in the literature before it reaches granted claims.
An R&D ontology strengthens semantic search further. An ontology is a structured map of technical concepts and their relationships. When semantic retrieval is organized through an ontology, the system interprets a query in the context of a technology domain rather than as isolated words, which improves both recall and precision.
What the shift changes for R&D and IP teams
Semantic search changes prior art and FTO work most directly. In prior art search, semantic retrieval surfaces conceptually relevant disclosures that keyword queries overlook, which strengthens both patentability assessments and invalidity arguments. In freedom-to-operate search, it surfaces active claims a product may read on even when those claims use unexpected language, reducing unquantified legal risk.
It also changes patent analytics. Once retrieval understands meaning, analytics can group filings by technical concept rather than by literal text, producing cleaner technology landscapes, competitor maps, and white space analysis. Agentic workflows build on this by chaining retrieval and reasoning steps to assemble landscapes, comparison matrices, and monitored positions automatically.
Where Cypris fits
Cypris is an AI-native R&D intelligence platform built on semantic search across a corpus of more than 500 million patents and scientific papers, organized through a proprietary R&D ontology. The ontology lets Cypris interpret technical meaning and retrieve conceptually related patents and literature at the claim level, rather than matching keywords.
Cypris Q, the platform's agentic layer, chains semantic retrieval and reasoning into end-to-end workflows such as landscape analysis, prior art review, and FTO assessment. Agentic Monitoring keeps those positions current by evaluating new filings as they publish. Cypris operates under enterprise API partnerships with OpenAI, Anthropic, and Google, with enterprise-grade security, and serves hundreds of enterprise customers across pharmaceuticals, chemicals, advanced materials, and other regulated industries.
FAQ
What is semantic search for patents?
Semantic search for patents retrieves filings by meaning rather than by exact keywords, representing text as vectors so that conceptually similar patents sit close together. This surfaces relevant patents that use different terminology than a query expects, which keyword search cannot do.
What is the difference between semantic search and keyword search?
Semantic search matches the meaning of text, while keyword search matches exact terms combined with Boolean operators. Keyword search misses filings that describe the same invention in different words, whereas semantic search retrieves them because it operates on concepts rather than literal strings.
Why are R&D teams moving to AI-native patent search?
R&D teams are moving to AI-native patent search because the volume and linguistic variety of global filings have outpaced keyword methods, causing silent gaps in coverage. Semantic search retrieves conceptually related filings across patents and scientific literature, reducing the risk that critical disclosures are missed.
Is semantic search better than keyword search for prior art?
Semantic search is generally stronger for prior art because it surfaces conceptually relevant disclosures that keyword queries overlook due to vocabulary mismatch. Keyword search remains useful for targeted lookups when the exact terminology is known, so many workflows combine both.
What is an R&D ontology in patent search?
An R&D ontology is a structured map of technical concepts and their relationships that organizes a search corpus by meaning. In patent search, an ontology lets a system interpret a query in the context of a technology domain rather than as isolated words, improving both recall and precision.
Does semantic search work across patents and scientific papers?
Semantic search works across both patents and scientific papers when the corpus unifies them, which matters because early technical disclosure often appears in the literature before it reaches granted patent claims. Searching both together produces a more complete technical and competitive picture.
How does semantic search improve patent analytics?
Semantic search improves patent analytics by grouping filings by technical concept rather than literal text, which produces cleaner technology landscapes, competitor maps, and white space analysis. Analytics built on meaning are more reliable than analytics built on keyword matches alone.
Can semantic patent search be automated with agents?
Semantic patent search can be automated with agentic workflows that chain retrieval and reasoning steps to assemble landscapes, comparison matrices, and monitored positions. Agents keep the analysis current by re-running semantic retrieval against new filings as they publish.
Does semantic search replace Boolean patent search entirely?
Semantic search does not fully replace Boolean patent search, because targeted keyword queries remain useful when exact terminology is known. The strongest workflows combine semantic retrieval for recall with keyword precision for confirmation.
What data coverage does effective semantic patent search require?
Effective semantic patent search requires broad coverage across patents and scientific literature, so that conceptually related disclosures in any vocabulary can be retrieved. A corpus of more than 500 million patents and scientific papers organized through an R&D ontology supports this breadth.
